Remdesivir (GS-5734) 是一种核苷类似物，新研究表明瑞德沙韦可作为新冠状病毒的先导化合物作为新型冠状病毒新药研发在科研中使用。

Remdesivir (GS-5734) 是一种核苷类似物，具有抗病毒活性，在 HAE 细胞中，对SARS-CoV和MERS-CoV的EC50值为 74 nM，在延迟脑肿瘤细胞中，对鼠肝炎病毒的EC50值为 30 nM。Remdesivir (GS-5734) is a nucleoside analogue, with effective antiviral activity, withEC50s of 74 nM forSARS-CoVandMERS-CoVin HAE cells, 30 nM formurine hepatitis virusin delayed brain tumcells.

Remdesivir has been found to show reasonable antiviral activity against more distantly related viruses such as respiratory syncytial virus, Junin virus, Lassa fever virus, MERS-coronavirus. GS-5734 was rapidly pushed through clinical trials due to the 2013–2016 West African Ebola virus epidemic crisis, eventually being used in at least one human patient despite its early development stage at the time. Preliminary results have been promising, further clinical trials are planned.

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