2,4-D乙酸乙酯

密度：

1.15g/cm3

熔点：

<-37ºC

沸点：

396.9ºC at 760mmHg

闪点：

137ºC

包装等级：

III

风险类别：

6.1(b)

CHEMICAL IDENTIFICATION

RTECS NUMBER :

AG8525000

CHEMICAL NAME :

Acetic acid, (2,4-dichlorophenoxy)-, 2-ethylhexyl ester

CAS REGISTRY NUMBER :

1928-43-4

BEILSTEIN REFERENCE NO. :

2293059

LAST UPDATED :

199706

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C16-H22-Cl2-O3

MOLECULAR WEIGHT :

333.28

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

300 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB85-143766 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

27300 mg/kg/13W-C

TOXIC EFFECTS :

Endocrine - changes in thyroid weight Blood - pigmented or nucleated red blood cells Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 33,161,1996

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Mammal - dog

DOSE/DURATION :

514 mg/kg/13W-C

TOXIC EFFECTS :

Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - changes in testicular weight

REFERENCE :

FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 29,78,1996 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

毒理学数据：

1、急性毒性：大鼠经口LD50： 300mg/kg；

2、其他多剂量毒性：大鼠经口TDLo：27300mg/kg/13W-I；狗经口TDLo：514mg/kg/13W-C。

 

计算化学数据

1.疏水参数计算参考值（XlogP）:无

2.氢键供体数量:0

3.氢键受体数量:3

4.可旋转化学键数量:10

5.互变异构体数量:无

6.拓扑分子极性表面积35.5

7.重原子数量:21

8.表面电荷:0

9.复杂度:299

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:1

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1