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磷酸氯非铵 基本信息
- 中文名称：
- 磷酸氯非铵
- 中文别名：
- 磷酸氯非铵
- 英文名称：
- Clofilium phosphate
- 英文别名：
- 4-(4-chlorophenyl)butyl-diethyl-heptylazanium,dihydrogen phosphate;
Clofilium phosphate (USAN/INN);
CLOFILIUM PHOSPHATE
- CAS No.：
- 68379-03-3
- 分 子 式：
- C63H111Cl3N3O4P
- 分 子 量：
- 1111.905901
- 精确分子量：
- 435.23100
- PSA：
- 90.40000
- 分子结构式：
-
- SDS：
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磷酸氯非铵 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CY9040890
- CAS REGISTRY NUMBER :
- 68379-03-3
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C21-H37-Cl-N.H2-O4-P
- MOLECULAR WEIGHT :
- 436.03
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Human
- DOSE/DURATION :
- 300 ug/kg
- TOXIC EFFECTS :
- Cardiac - arrhythmias (including changes in conduction)
- REFERENCE :
- NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2,
1983-84. For publisher information, see NCDREP. Volume(issue)/page/year:
2,103,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 33 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2,
1983-84. For publisher information, see NCDREP. Volume(issue)/page/year:
2,103,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
Behavioral - changes in motor activity (specific assay)
- REFERENCE :
- NDADD8 New Drugs Annual: Cardiovascular Drugs. (New York, NY) V.1-2,
1983-84. For publisher information, see NCDREP. Volume(issue)/page/year:
2,103,1984
