Section 1: Product Identification
Chemical Name: i-Propylmagnesium chloride, lithium chloride complex 1.3M (14wt% +/-1wt%) in tetrahydrofuran
CAS Registry Number: 745038-86-2
Formula: (CH3)2CHMgCl.LiCl
EINECS Number: 213-947-1
Chemical Family: grignard reagent
Synonym: Chloro(1-methylethyl)magnesium
Section 2: Composition and Information on Ingredients
Ingredient CAS Number Percent ACGIH (TWA) OSHA (PEL)
Title compound 745038-86-2 14% no data no data
THF 109-99-9 86% 200ppm 560mg/m3
Section 3: Hazards Identification
Extremely flammable. Reacts violently with moisture causing chemical burns on prolonged contact with human
Emergency Overview:
tissue. Harmful if swallowed. Causes burns. Possible risk of irreversible effects.
Primary Routes of Exposure: Ingestion, inhalation, skin, eyes
Eye Contact: Corrosive to eyes. May cause severe eye damage.
Skin Contact: Causes severe irritation and chemical burns with blistering and scarring.
Causes severe irritation of the nose, mucous membranes and respiratory tract . THF may cause nausea,
Inhalation:
dizziness, headache, drowsiness.
Ingestion: Harmful if swallowed. Ingestion causes severe burns to the mouth, throat and gastrointestinal tissues.
Corrosive to skin, eyes and respiratory tract. May cause severe eye damage. Skin contact causes burns with
Acute Health Affects:
scarring. Inhalation causes central nervous system depression.
Tetrahydrofuran is an eye and mucous membrane irritant and can cause liver and kidney damage. Prolonged
Chronic Health Affects: inhalation of the vapors may lead to respiratory disorders. Lithium poisoning may result in kidney and central
nervous system effects. Possible risk of irreversible effects.
NTP: No
IARC: No
OSHA: No
SECTION 4: First Aid Measures
Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need
Eye Exposure:
assistance in keeping their eye lids open. Get immediate medical attention.
Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if
Skin Exposure:
irritation persists.
Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty
Inhalation:
in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance.
Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce
Ingestion:
vomiting only if directed by medical personnel.
SECTION 5: Fire Fighting Measures
Flash Point: 1°F (THF)
Autoignition Temperature: 610°F (THF)
Explosion Limits: 1.8%(LEL), 11.8%(UEL) (THF
Extinguishing Medium: carbon dioxide, dry powder or foam
If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure
Special Fire Fighting Procedures:
self-contained breathing apparatus and full protective clothing.
Hazardous Combustion and If involved in a fire, this material may emit toxic and corrosive fumes.
Decomposion Products:
Unusual Fire or Explosion Hazards: Highly flammable. Vapors can form explosive mixtures with air. Hydrogen produced on contact with water.
SECTION 6: Accidental Release Measures
Eliminate all potential spark sources. Small spills can be absorbed into vermiculite or other chemical adsorbent
Spill and Leak Procedures:
suitable for flammable materials. Sweep up the mixture and dispose of properly.
SECTION 7: Handling and Storage
Store in a tightly sealed container under an inert atmosphere of nitrogen or argon. Keep in a cool, dry,
Handling and Storage:
well-ventilated place. Keep away from heat.
SECTION 8: Exposure Controls and Personal Protection
Eye Protection: Always wear approved safety glasses when handling a chemical substance in the laboratory.
Skin Protection: Wear protective clothing and gloves.
Ventilation: Handle the material in an efficient fume hood.
If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator
Respirator:
Protection Program to be in compliance with 29 CFR 1910.134.
Ventilation: Handle the material in an efficient fume hood.
Additional Protection: No additional protection required.
SECTION 9: Physical and Chemical Properties
Color and Form: yellow-brown liq.
Molecular Weight: 145.24
Melting Point: -108°C (THF)
Boiling Point: 66°C (THF)
Vapor Pressure: 143mmHg (20C) (THF)
Specific Gravity: 1.05
Odor: ethereal odor
Solubility in Water: reacts violently with water
SECTION 10: Stability and Reactivity
Stability: air sensitive, moisture sensitive
Hazardous Polymerization: no hazardous polymerization
Conditions to Avoid: heat, ignition sources and contact with moisture
Incompatibility: Acids, oxidizing agents, oxygen, water, alcohols, carbon dioxide, air
Decomposition Products: carbon monoxide, carbon dioxide, magnesium, lithium and hydrogen chloride, organic fumes
SECTION 11: Toxicological Information
Title compound: No information available in the RTECS files. THF: Inhalation(human); TCLo: 25000ppm.
Oral(rat); LD50: 1650mg/kg. Inhalation(rat); LC50: 21000ppm/3H. Intraperitoneal(rat); LD50: 2900mg/kg.
RTECS Data:
Inhalation(mouse); LCLo: 24000mg/m3/2H. Inhalation(rabbit); LC: >1200ppm/4H. Oral(guinea pig); LDLo:
500mg/kg. Inhalation(rat); TCLo: 1800ppm/6H/2Y-I.
Carcinogenic Effects: Insufficient data
Mutagenic Effects: THF: Possible mutagen
Tetratogenic Effects: THF: Reproductive effector
SECTION 12: Ecological Information
Ecological Information: No information available
SECTION 13: Disposal Considerations
Disposal: Dispose of according to local, state and federal regulations.
SECTION 14: Transportation
Shipping Name (CFR): Organometallic substance, Liquid, Water-reactive, Flammable
Hazard Class (CFR): 4.3
Additional Hazard Class (CFR): 3
Packaging Group (CFR): I
UN ID Number (CFR): UN# 3399
Shipping Name (IATA): Organometallic substance, Liquid, Water-reactive, Flammable
Hazard Class (IATA): 4.3
Additional Hazard Class (IATA): 3
Packaging Group (IATA): I
UN ID Number (IATA): UN# 3399
SECTION 15: Regulatory Information
TSCA: Listed in the TSCA inventory
SARA (Title 313): Not reportable under SARA 313
Second Ingredient: THF: Listed in the TSCA inventory. Not reportable under SARA 313.
SECTION 16 - ADDITIONAL INFORMATION
N/A
