丁氧卡因; 奥布卡因; 丁氧普鲁卡因; 4-氨基-3-丁氧基苯甲酸二乙基氨基乙基酯

密度：

1.052g/cm3

沸点：

446.9ºC at 760mmHg

闪点：

224.1ºC

折射率：

1.524

海关代码：

2922509090

CHEMICAL IDENTIFICATION

RTECS NUMBER :

DG1502000

CHEMICAL NAME :

Benzoic acid, 4-amino-3-butoxy-, 2-(diethylamino)ethyl ester

CAS REGISTRY NUMBER :

99-43-4

BEILSTEIN REFERENCE NO. :

2288926

LAST UPDATED :

199612

DATA ITEMS CITED :

4

MOLECULAR FORMULA :

C17-H28-N2-O3

MOLECULAR WEIGHT :

308.47

WISWESSER LINE NOTATION :

4OR BZ EVO2N2&2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

37 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

75 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

AACRAT Anesthesia and Analgesia (New York). (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) V.36- 1957- Volume(issue)/page/year: 38,265,1959

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

7800 ug/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 3,612,1953

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Bird - quail

DOSE/DURATION :

100 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 6,149,1982

中国海关编码：2922509090

概述：

2922509090. 其他氨基醇酚、氨基酸酚及其他含氧基氨基化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件：AB. 最惠国关税:6.5%. 普通关税:30.0%

申报要素：

品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

监管条件：

A.入境货物通关单B.出境货物通关单

检验检疫：

R.进口食品卫生监督检验S.出口食品卫生监督检验

摘要/Summary：

2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

分子结构数据

1、  摩尔折射率：89.72

2、  摩尔体积（cm³/mol）：292.9

3、  等张比容（90.2K）：738.5

4、  表面张力（dyne/cm）：40.4

5、  极化率（10-24cm3）：35.56

计算化学数据

1.疏水参数计算参考值（XlogP）:3.1

2.氢键供体数量:1

3.氢键受体数量:5

4.可旋转化学键数量:11

5.互变异构体数量:3

6.拓扑分子极性表面积64.8

7.重原子数量:22

8.表面电荷:0

9.复杂度:308

10.同位素原子数量:0

11.确定原子立构中心数量:0

12.不确定原子立构中心数量:0

13.确定化学键立构中心数量:0

14.不确定化学键立构中心数量:0

15.共价键单元数量:1