硫酸奎尼丁二水合物

  • 基本信息
  • 物化性质
  • 安全信息
  • 毒理性
  • MSDS
  • 表征图谱

硫酸奎尼丁二水合物 基本信息

中文名称:
硫酸奎尼丁二水合物 
中文别名:
硫酸奎尼丁二水合物;
奎尼定硫酸盐;
硫酸奎尼丁 
英文名称:
Quinidine sulfate dihydrate
英文别名:
Quinidine sulfate salt dihydrate;
Quinidine sulfate dihydrate 
CAS No.:
6591-63-5
分 子 式:
2(C20H24N2O2).H2SO4.2(H2O)
分 子 量:
782.94
精确分子量:
782.35600
PSA:
192.62000
MDL:
MFCD00149346
InChI:
InChI=1/2C20H24N2O2.H2O4S.2H2O/c2*1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;1-5(2,3)4;;/h2*3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;(H2,1,2,3,4);2*1H2/t2*13-,14-,19+,20-;;;/m00.../s1
危险品标志:
风险术语:
R22   
分子结构式:
SDS:
查看

硫酸奎尼丁二水合物 物化性质

熔点:
212-214 °C (dec.)(lit.)
沸点:
992.5ºC at 760 mmHg
闪点:
554ºC
折射率:
275 ° (C=2, 0.1mol/L HCl)

硫酸奎尼丁二水合物 安全信息

WGK_Germany:
3
德国有关水污染物质的分类清单
危险类别码:
R22
安全说明:
13-36
RTECS号:
VA5605000
危险标志:
Xn

硫酸奎尼丁二水合物 毒理性

CHEMICAL IDENTIFICATION

RTECS NUMBER :
VA5605000
CHEMICAL NAME :
Quinidine, hemisulfate, hydrate
CAS REGISTRY NUMBER :
6591-63-5
LAST UPDATED :
198708
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C20-H24-N2-O2.1/2H2-O4-S.H2-O
MOLECULAR WEIGHT :
391.52
WISWESSER LINE NOTATION :
T66 A B CNTJ A1U1 DYQ- ET66 BNJ HO1 2 &..H2.S-O4 &QH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
59 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 123,269,1958

硫酸奎尼丁二水合物 MSDS


Section 1. Chemical Product and Company Identification
    Quinidine sulfate dihydrate        Catalog    
    QU105
    Common Name/
    Number(s).
    Trade Name
    CAS#        6591-63-5    
    Manufacturer
    RTECS        VA5950000    
    SPECTRUM CHEMICAL MFG. CORP.
    TSCA        TSCA 8(b) inventory:    
    Quinidine sulfate dihydrate
    Commercial Name(s)        Not available.    
    CI# Not available.
    Synonym        6'-Methoxycinchonan-9-ol sulfate    
    IN CASE OF EMERGENCY
    Not available.
    Chemical Name
    Chemical Family        Not available.        CALL (310) 516-8000    
    (C20H24N2O2)2.H2SO4.2H2O
    Chemical Formula
    SPECTRUM CHEMICAL MFG. CORP.

Section 2.Composition and Information on Ingredients
    Exposure Limits
    TWA (mg/m3)        STEL (mg/m3) CEIL (mg/m3)    
    Name        CAS #        % by Weight    
    1) Quinidine sulfate dihydrate        6591-63-5        100    
    Toxicological Data        Quinidine sulfate dihydrate    
    on Ingredients        LD50: Not available.    
    LC50: Not available.

Section 3. Hazards Identification
    Potential Acute Health Effects Very hazardous in case of ingestion. Hazardous in case of eye contact (irritant), of inhalation.
    Potential Chronic Health        Very hazardous in case of ingestion.    
    Effects        Hazardous in case of skin contact (irritant), of eye contact (irritant), of inhalation.    
    CARCINOGENIC EFFECTS: Not available.
    MUTAGENIC EFFECTS: Not available.
    TERATOGENIC EFFECTS: Not available.
    DEVELOPMENTAL TOXICITY: Not available.
    Quinidine sulfate dihydrate

Section 4. First Aid Measures
    Eye Contact        Check for and remove any contact lenses. Immediately flush eyes with running water for at least 15 minutes,    
    keeping eyelids open. Cold water may be used. Do not use an eye ointment. Seek medical attention.
    Skin Contact        No known effect on skin contact, rinse with water for a few minutes.    
    Serious Skin Contact        Not available.    
    Inhalation        Allow the victim to rest in a well ventilated area. Seek immediate medical attention.    
    Serious Inhalation        Not available.    
    Ingestion        Do not induce vomiting. Loosen tight clothing such as a collar, tie, belt or waistband. If the victim is not    
    breathing, perform mouth-to-mouth resuscitation. Seek immediate medical attention.
    Serious Ingestion        Not available.    

Section 5. Fire and Explosion Data
    Flammability of the Product May be combustible at high temperature.
    Auto-Ignition Temperature Not available.
    Flash Points        Not available.    
    Flammable Limits        Not available.    
    Products of Combustion        These products are carbon oxides (CO, CO2), nitrogen oxides (NO, NO2...), sulfur oxides (SO2, SO3...).    
    Fire Hazards in Presence of Not available.
    Various Substances
    Explosion Hazards in Presence Risks of explosion of the product in presence of mechanical impact: Not available.
    of Various Substances        Risks of explosion of the product in presence of static discharge: Not available.    
    Fire Fighting Media        SMALL FIRE: Use DRY chemical powder.    
    and Instructions        LARGE FIRE: Use water spray, fog or foam. Do not use water jet.    
    Special Remarks on        Not available.    
    Fire Hazards
    Special Remarks on Explosion Not available.
    Hazards

Section 6. Accidental Release Measures
    Small Spill        Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by    
    spreading water on the contaminated surface and dispose of according to local and regional authority
    requirements.
    Large Spill        Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water    
    on the contaminated surface and allow to evacuate through the sanitary system.
    Quinidine sulfate dihydrate

Section 7. Handling and Storage
    Precautions        Keep away from heat. Keep away from sources of ignition. Empty containers pose a fire risk, evaporate the    
    residue under a fume hood. Ground all equipment containing material. Do not breathe dust. Avoid contact with
    eyes Wear suitable protective clothing In case of insufficient ventilation, wear suitable respiratory equipment If
    you feel unwell, seek medical attention and show the label when possible.
    Storage        Keep container dry. Keep in a cool place. Ground all equipment containing material. Keep container tightly    
    closed. Keep in a cool, well-ventilated place. Combustible materials should be stored away from extreme heat
    and away from strong oxidizing agents.

Section 8. Exposure Controls/Personal Protection
    Engineering Controls        Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below    
    recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to
    airborne contaminants below the exposure limit.
    Personal Protection        Splash goggles. Lab coat.    
    Personal Protection in Case of Splash goggles. Full suit. Boots. Gloves. Suggested protective clothing might not be sufficient; consult a
    a Large Spill        specialist BEFORE handling this product.    
    Exposure Limits        Not available.    

Section 9. Physical and Chemical Properties
    Physical state and appearance Solid. (Crystals solid.)        Odor        Odorless.    
    Taste        Bitter.    
    Molecular Weight        782.96 g/mole    
    Color        White.    
    pH (1% soln/water)        Not available.    
    Not available.
    Boiling Point
    Melting Point        Decomposes. (120°C or 248°F)    
    Not available.
    Critical Temperature
    Specific Gravity        Not available.    
    Vapor Pressure        Not applicable.    
    Vapor Density        Not available.    
    Volatility        Not available.    
    Odor Threshold        Not available.    
    Water/Oil Dist. Coeff.        Not available.    
    Ionicity (in Water)        Not available.    
    Dispersion Properties        See solubility in water, methanol.    
    Solubility        Soluble in methanol.    
    Partially soluble in cold water.

Section 10. Stability and Reactivity Data
    Stability        The product is stable.    
    Not available.
    Instability Temperature
    Conditions of Instability        Not available.    
    Incompatibility with various Not available.
    substances
    Quinidine sulfate dihydrate
    Corrosivity        Non-corrosive in presence of glass.    
    Special Remarks on        Not available.    
    Reactivity
    Special Remarks on        Not available.    
    Corrosivity
    Polymerization        No.    

Section 11. Toxicological Information
    Routes of Entry        Eye contact. Inhalation. Ingestion.    
    Toxicity to Animals        LD50: Not available.    
    LC50: Not available.
    Chronic Effects on Humans Not available.
    Other Toxic Effects on        Very hazardous in case of ingestion.    
    Humans        Hazardous in case of inhalation.    
    Special Remarks on        Not available.    
    Toxicity to Animals
    Special Remarks on        Human: passes through the placenta, excreted in maternal milk.    
    Chronic Effects on Humans
    Special Remarks on other        Not available.    
    Toxic Effects on Humans

Section 12. Ecological Information
    Ecotoxicity        Not available.    
    BOD5 and COD        Not available.    
    Products of Biodegradation        Possibly hazardous short term degradation products are not likely. However, long term degradation products may    
    arise.
    Toxicity of the Products        The products of degradation are more toxic.    
    of Biodegradation
    Special Remarks on the        Not available.    
    Products of Biodegradation

Section 13. Disposal Considerations
    Waste Disposal

Section 14. Transport Information
    DOT Classification        Not a DOT controlled material (United States).    
    Identification        Not applicable.    
    Special Provisions for        Not applicable.    
    Transport
    Quinidine sulfate dihydrate
    DOT (Pictograms)

Section 15. Other Regulatory Information and Pictograms
    TSCA 8(b) inventory: Quinidine sulfate dihydrate
    Federal and State
    Regulations
    California
    Proposition 65
    Warnings
    Other Regulations        Not available..    
    WHMIS (Canada) Not controlled under WHMIS (Canada).
    Other Classifications
    DSCL (EEC)        R36- Irritating to eyes.    
    Health Hazard
    HMIS (U.S.A.)        2 National Fire Protection    
    1 Flammability
    1 Association (U.S.A.)
    Fire Hazard
    2 0 Reactivity
    Health
    Reactivity
    0
    Specific hazard
    Personal Protection
    j
    WHMIS (Canada)
    (Pictograms)
    DSCL (Europe)
    (Pictograms)
    TDG (Canada)
    (Pictograms)
    ADR (Europe)
    (Pictograms)
    Protective Equipment
    Not applicable.
    Lab coat.
    Not applicable.
    Splash goggles.


SECTION 16 - ADDITIONAL INFORMATION
N/A

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