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阿库氯铵 基本信息
- 中文名称：
- 阿库氯铵
- 中文别名：
- 阿库氯铵
- 英文名称：
- 10H,21H-1,21:10,12-Diethano-19aH,20bH-dipyrrolo[3,2-f:3',2'-f'][1,5]diazocino[3,2,1-jk:7,6,5-j'k']dicarbazolium,2,3,11,11a,13,14,22,22a-octahydro-23,26-bis(2-hydroxyethylidene)-1,12-di-2-propen-1-yl-,chloride (1:2), (1R,3aS,10S,11aS,12R,14aS,19aS,20bS,21S,22aS,23E,26E)-
- 英文别名：
- Alcuronium Chloride;
Alcuronium;
Alcuronium dichloride
- CAS No.：
- 15180-03-7
- 分 子 式：
- C44H50N4O2.2Cl
- 分 子 量：
- 737.88
- 精确分子量：
- 736.33100
- PSA：
- 46.94000
- EINECS：
- 239-229-8
- 安全术语：
- Poison by ingestion, intraperitoneal, subcutaneous, and intravenous routes. Used as a skeletal muscle relaxant. When heated to decomposition it emits very toxic fumes of NOx and Cl−. See also ALLYL COMPOUNDS.
- 分子结构式：
-
- SDS：
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阿库氯铵 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- RC9868000
- CHEMICAL NAME :
- Nortoxiferinium, N,N'-diallyl-, dichloride
- CAS REGISTRY NUMBER :
- 15180-03-7
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 7
- MOLECULAR FORMULA :
- C44-H50-N4-O2.2Cl
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27600 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 270 ug/kg
- TOXIC EFFECTS :
- Behavioral - muscle weakness
Lungs, Thorax, or Respiration - dyspnea
- REFERENCE :
- GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?).
Volume(issue)/page/year: 1,349,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 280 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 38500 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?).
Volume(issue)/page/year: 1,349,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 610 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 610 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GNRIDX Gendai no Rinsho. (Tokyo, Japan) V.1-10, 1967-76(?).
Volume(issue)/page/year: 1,349,1967
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180,
Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 3,390,1969
