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盐酸阿芬他尼 基本信息
- 中文名称：
- 盐酸阿芬他尼
- 中文别名：
- 盐酸阿芬他尼
- 英文名称：
- Propanamide,N-[1-[2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)-4-piperidinyl]-N-phenyl-,hydrochloride (1:1)
- 英文别名：
- ALFENTANIL HYDROCHLORIDE;
N-[1-[2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide hydrochloride;
N-[1-[2-(4-Ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl]-4-(methoxymethyl)-4-piperidinyl]-N-phenyl-propanamide Hydrochloride;
N-<1-<2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)ethyl>-4-(methoxymethyl)-4-piperidinyl>-N-phenylpropanamide monohydrochloride;
alfentanyl hydrochloride;
Alfentanilhydrochlorid;
N-[1-(2-(4-ethyl-5-oxo-4,5-dihydro-1H-tetrazol-1-yl)ethyl)-4-(methoxymethyl)piperidin-4-yl]-N-phenylpropionamide hydrochloride;
Alfenta (tn);
Alfentanil hydrochloride (usp)
- CAS No.：
- 69049-06-5
- 分 子 式：
- C21H32N6O3.ClH
- 分 子 量：
- 452.98
- 精确分子量：
- 452.23000
- PSA：
- 85.49000
- EINECS：
- 273-846-3
- InChI：
- The Key: AQORHZJDCHLLJN-UHFFFAOYSA-N
- 风险术语：
- 11-23/24/25-39/23/24/25
- 分子结构式：
-
- SDS：
- 查看
盐酸阿芬他尼 物化性质
- 熔点：
- 92-94?C
- 沸点：
- 511.8ºC at 760 mmHg
- 闪点：
- 263.3ºC
盐酸阿芬他尼 毒理性
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX1452500
- CHEMICAL NAME :
- Propanamide,
N-(1-(2-(4-ethyl-4,5-dihydro-5-oxo-1H-tetrazol-1-yl)e
thyl)-4-(methoxymethy l)- 4-piperidinyl)-N-phenyl-,
hydrochloride, hydrate
- CAS REGISTRY NUMBER :
- 69049-06-5
- LAST UPDATED :
- 199109
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H32-N6-O3.Cl-H.H2-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 47500 ug/kg
- TOXIC EFFECTS :
- Behavioral - analgesia
- REFERENCE :
- DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New
York, NY 10003) V.1- 1981- Volume(issue)/page/year: 1,83,1981
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - other (direct) parasympathomimetic
Behavioral - altered sleep time (including change in righting reflex)
Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- DDREDK Drug Development Research. (Alan R. Liss, Inc., 41 E. 11th St., New
York, NY 10003) V.1- 1981- Volume(issue)/page/year: 1,83,1981
